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3-2.Atopic disposition |
Constitution that makes IgE antibody easily
Does the IgE antibody relate being inherited to the constitution that makes
the IgE antibody easily?The type allergy (immediate type) is said and the
constitution that develops easily is said. As for the person where the
blood level of the IgE antibody of a normal adult has the atopic disposition
though is 150 an international in bloody 1ml unit (About 2.3 Nano gram
= Nano gram is the ninth power of ten worth of one gram) and is a very
small amount, this increases. Therefore, the antigen adheres to the IgE
antibody that unites with the gemastete cell when the IgE antibody adheres
on the film of the gemastete cell that exists in the body, and the antigen
(allergen) enters the inside of the body again, the gemastete cell breaks
because of the stimulation, and itchy of histamine etc. and the material
that causes the inflammation come out from the inside.
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Antigen
Phlegm white material that causes allergy. The protein unites with the metal in a metallic allergy etc. and it becomes an antigen. It is synonymous with the allergen.
Antibody
Protein material in blood that unites with antigen by couple 1. It is said immunoglobulin
(Ig=Immuno globulin). There is working that adheres to the antigen of the
foreign body that becomes harm for bodies such as viruses and bacilli and
attacks the antibody usually. The vaccination etc. use this working. |
However, the allergy occurs when produced excessively exceeding a normal range. Moreover, the element that originally has it not an outside foreign body but for myself is recognized as an antigen, and the one to make the antibody is called 'Autoimmune disease'. |
Kind of antibody
There are five kinds of antibodies (immunoglobulin)(IgG, IgA, IgM, IgE,
and IgD). The IgE antibody that relates to the allergy only accounts for
0.002% of the immunoglobulin inside if it is normal. The IgE antibody is
called an antibody that causes the allergy by htype in these antibodies.
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There is an inheritance in the background of the atopic constitution.
It can be said that the person who causes atopic dermatitis is a constitution
that makes the IgE antibody easily. There is the inherited one in the background.
It can be said that it has the factor that becomes atopic dermatitis easily
when parents and siblings, etc. have the people such as the bronchial asthma,
the allergy coryza, and atopic dermatitis. When the parents either is the
atopic constitutions, about 60% is said that it will become an atopic constitution
establishment of about 80% when it is parents and the atopic constitution.
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