7-8.Changing of dermis
	Collagen fiber and Erastin fiber's being regularly arranging it in is filled with Muco polysaccharides such as hyaluronic acids and the dermatan sulphates as for dermis, and elasticity and flexibility have been brought by the skin.
	Change by aging �@The entire amount of collagen and Erastin decreases. �ACollagen becomes thin, the solubility collagen decreases, and no solubleness collagen increases. �BErastin at the intersection of collagen cannot be reproduced, too. �CThe moisture several thousand times weight of I is saved in the Muco polysaccharide, and the number of hyaluronic acids of the character that moisture is not missed decreases.
	The elasticity of the skin is lost because of a decrease of collagen, Erastin, and the Muco polysaccharide, and the amount of moisture that the skin has decreases sharply. The change in the quality of the constitution of dermis not only relates greatly to the generation of the wrinkle but also because this influence influences the epidermal soon, is related to the dryness of the skin.
	Solubility collagen and no solubleness collagen ●There are two kinds of collagen (solubility and no solubleness).
	（Solubility collagen) It is collagen that excels in the moisture absorption, and keeps the beam and the elasticity of the skin. （No solubleness collagen） Collagen by which fiber becomes hard is said. The solubility collagen is changed into no solubleness collagen by aging and ultraviolet rays.