8-6.Cause of wrinkle：Inflammation
	As for the inflammation of the skin, it poisons, and even if the level is light, the damage to the skin grows as swelling etc. as for the chronicity. Connective tissue of dermis loses revitalization, and it becomes inelastic. Moreover, if the medicine such as ointments to cure the inflammation doesn't correctly use a proper amount, the skin might be influenced harmfully.