2-5.Primary irritation Contact, dermatitis and 　　　Allergy,Contact, dermatitis
	Primary irritation Contact, dermatitis ●The material that becomes the factor of Primary irritation Contact and dermatitis is said, "Contact poison". For instance, cosmetics not appropriate for the plant, the insect, and the skin with the chemical and the toxicitys such as the acids and the alkalis with a strong action and harmful sunrays, etc. are said.Everyone causes Cabre when defeated at stimulation external the resistance power of the skin because it is a material that the one gives the skin strong stimulation, the amount is large, it is high density, and the contact time is long.
					●The individual variation of Cabre with cosmetics is large, and the spice, oils and fats, the coloring matter, and the oil system surface-active agent, etc. included in cosmetics have the possibility of becoming a stimulation factor. In general, it can be said that cream, the milky lotion, and the foundation that sticks to the skin than the make-up cosmetics will cause poisoning easily. It is said as causing the allergic reaction to show a hypersensitive reaction only in a certain specific material especially though there is a possibility that various materials included in cosAnd, dermatitis that the allergic reaction is caused by the contact material is said,". metics become factors of external stimulation.
	Allergy,Contact, dermatitis ●It is a reaction that takes place only to a special person who has the antibody corresponding to the stimulus quality (antigen). There is what the cause doesn't remember either a lot because it happens while stimulate being repeated several times without happening in contact the symptom's appearing after 48 hours have passed from 24 since it came in contact, and once. The stimulus quality (antigen) is not a reaction that depends at the amount and the contact time but a qualitative reaction. It is likely to react because of an inherent allergic constitution. Moreover, it might become easy for poisoning to occur because the hormone balance such as the pregnancy period and the change of life collapses before and behind the menstruation.