5-1.Mechanism to be able to do acne
	Acne is made the face, the chest, and aEspecially, there are a lot of making at adolescence when various hormonal secretions become active, and, in this case, it does because of an excessive sebum secretion by activating the hormone according to the second character signs. However, adult acne has various causes like the stress, the make-up dirt, and eating habits, etc. back in general, with a lot of sebum gland. It is easy to make it to a fatty skin.
					Until acne is generated �@It is given that sebum gland is stimulated by an increase of the male hormone and the amount of the secretion increases rapidly. �AWhen the number of bacilli in hair follicle increases, sebums collected on the inside are resolved, and "Non-esterified fatty acid" increases, hair follicle is stimulated. ※"Propionibacterium acne" that is called an acne bacterium that is eternal epidermal Kin lives and "Staphylococcus aureus" and "Staphylococcus epidermidis" start proliferating internally. As for this proliferating bacillus, production begins to see the material of bacillus lipase (enzyme that presses the resolution). The lipase is production life . that resolves sebum intermediate middle fat as for "Non-esterified fatty acid" that is the inflammation cause material. �BStratum corneum around hair follicle comes for the keratinization doing and the hair entrance to tend to be narrowed thick and to stagnate. �CIt becomes a lipid peroxide, garbage and dust adhere additionally, breeding of the bacillus becomes active, and the lipid that passes time and is saved up is angry
					The first acne formation stage ＜White acne＞ ●The state that hair follicle is narrowed at the start of acne and sebum collects in hair follicle is called a comedo. The comedo is a small, hard papula that the first stage looks white from a normal skin on the surface a little. Of stickiness like white when pushing by the tip of a finger. Most is saved sebum. The nasty smell might be attended because it has already oxidized, and it changes in quality. The comedo to which hair follicle has not opened yet is said, 'White acne' like white like this. This time is not angry yet. Because contents of the comedo do not touch air, the autumn tint might not be attended. .
					Acne formation second stage ＜Black acne> ●When white acne advances further, sebum collected in hair follicle pushes and expands the hair entrance. Dirt in air outside adheres, and sebum oxidizes, and the part at the hair entrance becomes blackish. This is said, 'Black acne'.
					The third acne formation stage ＜Inflammation＞ ●It is angry because of stimulation and the bacillus by the sebum element and becomes acne.
	＜Bacillus＞ Abounding as a bacterium that always exists in the skin reaches from many hundreds of a cm several hundred thousand pieces by "Staphylococcus epidermidis" which is a kind of the staphylococcus. Next, it becomes units of many hundreds of from tens of by the acne bacterium that is called "Acne bacillus". Because either bacterium also likes fat, sebum becomes a splendid object. In addition, the more it advances by the close of the hair entrance because the acne bacillus is a bacillus that dislikes touching air, the more it proliferates in hair follicle. ＜Stimulation of sebum element＞ Sebum collected in hair follicle is changed into 'Non-esterified fatty acid' that gives skin cells strong stimulation in these bacilli when resolved. Becoming 'Red acne' when comedo is angry, and when red acne suppurates, pustule can be done, and this is 'Yellow acne'
					The fourth acne formation stage ＜Induration　contused　waund＞ ●It recovers without leaving according to appropriate treatment, clean maintenance, and the regular life, etc. when the pustule of yellow acne has been settled on the surface of the skin. However, when the inflammation arrives even at the corium and the hypodermis-subcutaneous tissue, the cell is destroyed.The state of the serious illness of acne is called 'Induration contused waund'. Like Crater will be left back when the pain and itchy are accompanied, and it leaves it as it is. Appropriate treatment is necessary in the consultation of dermatology.